Gavage-Related Reflux in Rats

Reflux esophagitis in war-related sulfur mustard lung disease

  Background: Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago.   Methods : One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. Of them, 52 cases had been e...

Changes in Ghrelin-Related Factors in Gastroesophageal Reflux Disease in Rats

To examine gastrointestinal hormone profiles and functional changes in gastroesophageal reflux disease (GERD), blood levels of the orexigenic hormone ghrelin were measured in rats with experimentally induced GERD. During the experiment, plasma acyl ghrelin levels in GERD rats were higher than those in sham-operated rats, although food intake was reduced in GERD rats. Although plasma levels of t...

Effects of oral gavage treatment of Eupatilin on protection of skin flaps in rats

Introduction: Nowadays, skin flaps are used to repair wounds, skin lesions and in reconstructive surgeries. In this way, the main problem is loss of flap tissue and necrosis, due to processes that result from ischemia-reperfusion injury and reactive oxygen species. Eupatilin is an O-methylated flavone derived from Artemisia plants that demonstrates anti-inflammatory, anti-oxidative, and anti-tu...

Postprandial Changes in High Density Lipoproteins in Rats Subjected to Gavage Administration of Virgin Olive Oil

BACKGROUND AND AIMS The present study was designed to verify the influence of acute fat loading on high density lipoprotein (HDL) composition, and the involvement of liver and different segments of small intestine in the changes observed. METHODS AND RESULTS To address these issues, rats were administered a bolus of 5-ml of extra-virgin olive oil and sacrificed 4 and 8 hours after feeding. In...

Éditorial: Gavage des oies